胆宁片治疗胆源性消化不良的临床研究

费春明

[摘要] 目的 分析胆宁片治疗胆源性消化不良的临床效果。方法 方便选择该院自2013年5月—2017年5月收治的101例胆源性消化不良患者，将其随机分为2组，对照组50例，观察组51例。对照组患者给予铝碳酸镁治疗，观察组给予胆宁片进行治疗，对比2组患者治疗效果。结果 在治疗前两组患者各项评分均差异无统计学意义（P>0.05）。随着治疗的进行，2组患者的各项评分一直在下降，但对照组患者下降幅度没有对照组明显（P<0.05）。观察组患者第1周有效率为39.23%，第2周为90.20%，第4周为100.00%均明显高于对照组的22.00%、46.00%、62.00%，相对比差异有统计学意义（P<0.05）。观察组患者复发率为9.80%、不良反应发生率为6.88%，对照组分别为为8.00%、4.00%，相对比差异无统计学意义（P>0.05。结论 要有效的将胆源性消化不良所致的腹痛、食欲不振、腹胀早饱等不适症状改善，缓解患者存在的便秘现象，采用胆宁片是不错的选择。

[关键词] 胆宁片；胆源性消化不良；临床疗效

[中图分类号] R259 [文献标识码] A [文章编号] 1674-0742（2017）10（c）-0119-03

Clinical Study on Treatment of Biliary Dyspepsia with Danning Tablets

FEI Chun-ming

Gastroenterology Department， Liuhe District Peoples Hospital， Nanjing， Jiangsu Province， 211500 China

[Abstract] Objective This paper tries to analyze the clinical effect of danning tablet in the treatment of biliary dyspepsia. Methods 101 patients with cholestatic dyspepsia from May 2013 to May 2017 were convenient selected and randomly divided into two groups： the control group （n=50）and the observation group （n=51）. The patients in the control group were treated with magnesium aluminum carbonate. The observation group was treated with danning tablets and the treatment effect of the two groups were compared. Results There were no significant differences in the scores of the two groups before treatment（P>0.05）. With the progress of the treatment， the scores of the two groups of patients had been declining， but the control group did not decrease so much as the observation group（P<0.05）. The effective rate was 39.23% in the first week and 90.20% in the second week and 100.00% in the fourth week， significantly higher than those in the control group of 22.00%， 46.00%， 62.00%， The difference was signitically significant（P<0.05）. The recurrence rate was 9.80% in the observation group and 6.88% of the adverse reaction， while those in the control group were 8.00% and 4.00%. The difference was not significant（P>0.05）. Conclusion The danning tablet can effectively handle the bile endemic caused by abdominal pain， loss of appetite， abdominal distension and early discomfort and other symptoms， relieve the existence of constipation in patients.

[Key words] Danning tablet； Biliary dyspepsia； Clinical efficacy

慢性膽囊炎、胆囊结石及胆囊术后综合症等所致的消化不良均属于胆源性消化不良。该疾病是由胆汁分泌异常引起，胆汁可使脂肪乳化成脂肪微粒的速度加快，将胰液中胰腺脂肪酶作用面积增加。要有效的改善胆源性消化不良所致的症状，需将消化酶进行补充，进而使分泌的胆汁充足；还需将患者的胃肠蠕动能力进行恢复[1-2]。中药胆宁片能促使胆汁的分泌，还可使得胃肠功能的恢复加速，现方便选择该院自2013年5月—2017年5月收治的101例患者作为研究，现报道如下。endprint