参附注射液在第二产程中应用的临床研究

郑赣红+赵令睿+吴云根+杜永艳+郑程静子+李红梅

[摘要] 目的 探讨参附注射液在第二产程中的应用效果。方法 选择2017年1～5月在德兴市中医院住院分娩的80例初产妇作为研究对象，采用随机数字表法分为观察组、对照组，每组40例。观察组于第二产程开始给予5%葡萄糖500 ml+参附注射液40 ml静脉点滴，对照组于第二产程开始给予5%的葡萄糖500 ml静脉点滴。比较两组的第二产程时间、新生儿1 min Apgar评分及产后出血量。结果 观察组的第二产程时间短于对照组，新生儿1 min Apgar评分高于对照组，差异有统计学意义（P<0.05）；观察组产妇产时、产后出血量均明显少于对照组，差异有统计学意义（P<0.05）。结论 参附注射液能缩短第二产程，减少产后出血，提高新生儿评分，为中医中药更广泛的临床应用提供依据，为临床治疗提供新方法。

[关键词]参附注射液；第二产程；应用效果；Apgar评分；出血量

[中图分类号] R289.3 [文献标识码] A [文章编号] 1674-4721（2017）09（c）-0079-03

[Abstract]Objective To investigate the application effect of Shenfu Injection in the second stage of labor.Methods 80 primiparae with hospital delivery in Traditional Chinese Medicine Hospital of Dexing City from January to May 2017 were selected as the research object，and they were divided into observation group and control group according to random number table method，and there were 40 cases in each group.Observation group was given 5% Glucose 500 ml plusing intravenous drip of Shenfu Injection 40 ml in the second stage of labor，while control group was given intravenous drip of 5% Glucose 500 ml in the second stage of labor.The time of second stage of labor，Apgar 1 min score and postpartum bleeding volume were compared between the two groups.Results The time of second stage of labor in observation group was shorter than that in control group，and Apgar 1 min score was higher than that in control group （P<0.05）.The intrapartum and postpartum bleeding volume of observation group were significantly fewer than those of control group （P<0.05）.Conclusion Shenfu Injection can shorten the second stage of labor，reduce postpartum bleeding and improve Neonatal score.It can provide basis for more extensive application of traditional Chinese medicine and provide new methods for clinical treatment.

[Key words]Shenfu Injection；The second stage of labor；Application effect；Apagr score；Bleeding volume

分娩是大部分女性均会经历的一个生理过程，但很多产妇在分娩过程中会发生诸多不良事件，尤其是第二产程时，产妇身心均会出现一系列改变，如呼吸急促、心率加快、肺内气体交换不足等，致使子宫收缩乏力，胎先露下降受阻，产程延长，产妇体力大量消耗等，子宫收缩乏力易造成產后出血等不良事件的发生，对母婴安全造成极大威胁[1]。第二产程是分娩过程中的重要环节，有效缩短第二产程时间是保障母婴安全、缓解产妇疼痛、改善母婴结局的关键[2]。在实际的妇产科临床中，如何缓解产妇紧张感与疼痛感、提高自然分娩率、缩短产程、减少产后不良事件发生是目前临床急需解决的问题[3-4]。本研究旨在探讨参附注射液在第二产程中的应用效果，现报道如下。

1资料与方法

1.1 一般资料

选择2017年1～5月在德兴市中医院住院分娩的80例初产妇作为研究对象，本研究经我院医学伦理委员会批准。根据随机数字表法将患者分为观察组、对照组，每组40例。观察组年龄21～33岁，平均（26.33±2.51）岁；孕龄37～41周，平均（39.12±0.78）周；体重50～78 kg，平均（62.47±5.61）kg。对照组年龄22～32岁，平均（26.68±2.74）岁；孕龄36～41周，平均（38.87±0.93）周；体重51～78 kg，平均（63.05±5.89）kg。两组一般资料比较，差异无统计学意义（P>0.05），具有可比性。endprint