稳心颗粒联合美托洛尔治疗冠心病合并室性心律失常的疗效分析

杜慧锋

[摘要] 目的 分析穩心颗粒联合美托洛尔治疗冠心病合并室性心律失常的临床疗效。方法 方便选择2017年1月—2018年2月来该院就诊的148例冠心病合并室性心律失常的患者，根据随机分组的原则平均分为两组，即观察组与对照组，各74例。对照组患者采用单纯美托洛尔进行治疗，观察组的患者则在对照组基础上加用稳心颗粒进行联合治疗，观察并比较两组的治疗效果。结果 经过数据处理后，观察组患者74例中显效23例、有效44例、无效7例，总有效率为90.54%，对照组患者74例中显效18例、有效34例、无效22例，总有效率70.27%，差异有统计学意义（χ2=9.649，P=0.003<0.05）。对照组患者74例中发生恶心11例、呕吐8例、同时发生3例，总不良反应发生率为21.62%，观察组患者74例中恶心4例、呕吐3例、同时发生1例，总不良反应发生率为8.11%，差异有统计学意义（χ2=5.339，P=0.036<0.05）。结论 稳心颗粒联合美托洛尔治疗冠心病合并室性心律失常疗效显著，显著改善患者生理功能，值得在临床大力推广。

[关键词] 稳心颗粒;美托洛尔;冠心病合并室性心律失常;疗效

[中图分类号] R541          [文献标识码] A          [文章编号] 1674-0742（2019）11（a）-0087-03

Therapeutic Effect of Wenxin Granule Combined with Metoprolol in the Treatment of Coronary Heart Disease Complicated with Ventricular Arrhythmia

DU Hui-feng

Department of Cardiology， Jilin Provincial People's Hospital， Changchun， Jilin Province， 130021 China

[Abstract] Objective To analyze the clinical efficacy of Wenxin granule combined with metoprolol in the treatment of coronary heart disease with ventricular arrhythmia. Methods A total of 148 patients with coronary heart disease complicated with ventricular arrhythmia who came to the hospital from January 2017 to February 2018 were Conveniently selected and divided into two groups according to the principle of randomization， namely the observation group and the control group， with 74 cases each. The patients in the control group were treated with metoprolol alone. The patients in the observation group were treated with Wenxin granules on the basis of the control group. The therapeutic effects of the two groups were observed and compared. Results After data processing， the observation group was markedly effective in 23 cases， effective in 44 cases， and ineffective in 7 cases. The total effective rate was 90.54%. In the control group， 74 cases were markedly effective in 18 cases， effective in 34 cases， and ineffective in 22 cases. The total effective rate was 70.27%. The difference was statistically significant（χ2=9.649，P=0.003<0.05）. In the control group， there were 11 cases of nausea， 8 cases of vomiting， and 3 cases of simultaneous vomiting. The total adverse reaction rate was 21.62%. In the observation group， 74 cases of nausea， 4 cases of vomiting， 3 cases of vomiting， and 1 case of total adverse reactions were observed. The reaction rate was 8.11%， The difference was statistically significant（χ2=5.339，P=0.036<0.05）. Conclusion Wenxin granule combined with metoprolol is effective in the treatment of coronary heart disease with ventricular arrhythmia， and significantly improves the physiological function of patients. It is worthy of promotion in clinical practice.