邹春玲
[摘要] 目的 分析稳心复脉汤对冠心病患者QT间期离散度的影响。 方法 方便选取该院2013年1月—2015年10月期间收治的95例冠心病患者分为两组,对照组45例单纯常规治疗,观察组50例在单纯常规基础上稳心复脉汤治疗。观察两组患者胸闷、胸痛、气短、乏力等冠心病症状变化,监测QT离散度变化。对比两组患者治疗效果。 结果 观察组总有效率98%高于对照组总有效率80%,观察组治疗后总症候评分(0.82±0.31)分及QT间期离散度(67.9±13.9)ms较对照组治疗后总症候评分(3.85±0.82)分及QT间期离散度(51.0±12.9)ms降低(P<0.05)。结论 稳心复脉汤能降低冠心病患者QT间期离散度,改善患者冠心病心肌缺血症状,从而达到预防恶性心律失常发生的作用。
[关键词] 稳心复脉汤;冠心病;QT间期离散度
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2017)02(c)-0177-03
Effect of Wenxin Fumain Tang on the Dispersion of Patients with Coronary Heart Disease during the QT Interval
ZOU Chun-ling
Yantai Sanatorium of Shengli Petroleum Administration, Yantai, Shandong Province, 264001 China
[Abstract] Objective To analyze the effect of Wenxin Fumain Tang on the dispersion of patients with coronary heart disease during the QT interval. Methods Convenient selection 95 cases of patients with coronary heart disease admitted and treated in our hospital from January 2013 to October 2015 were selected, the control group(n=45) adopted the routine treatment, while the observation group(n=50) adopted the Wenxin Fumain Tang on the basis of the routine treatment, and the symptoms of chest tightness, chest pain, shortness of breath and fatigue were compared between the two groups, and the QT dispersion change was monitored and the treatment effect was observed. Results The total effective rate in the observation group was higher than that in the control group(98% vs 80%), and the total symptom score and QT interval dispersion in the observation group decreased compared with those in the control group after treatment, [(0.82±0.31)points, (67.9±13.9)ms vs (3.85±0.82)points, (51.0±12.9)ms](P<0.05). Conclusion The Wenxin Fumain Tang can decrease the dispersion of patients with coronary heart disease during the QT interval and improve the myocardial ischemic symptoms of patients with coronary heart disease thus preventing the occurrence of malignant arrhythmia.
[Key words] Wenxin Fumain Tang; Coronary heart disease; QT interval dispersion
冠心病多見于中老年人群,患者伴复杂性心律失常、胸闷、心悸等症状,病情呈进行性发展,甚至会诱发患者猝死。QT间期离散度(QTd)表现为体表12导联心电图各导联之间最长和最短QT间期的差异程度(最长的QT间期与最短的QT间期之间的差值),能间接性反映患者心室肌复极化的不一致性及不稳定性的变化程度,逐渐成为预测病人发生严重室性心律失常和猝死的主要标志[1]。通过对该院2013年1月—2015年10月期间收治的95例冠心病患者的临床观察,QT间期离散度的判断,力求研究稳心复脉汤对冠心病患者心电图QTd的影响及对心肌缺血的改善作用,判断患者病情恢复及预后程度。
1 资料与方法
1.1 一般资料
方便选取该院收治的冠心病患者95例,随机双盲法分为两组,观察组50例,男31例,女19例;年龄40~80岁,平均(58.9±13.0)岁;对照组45例,男29例,女16例;年龄40~82岁,平均(60.1±12.6)岁;与《实用内科学》[2]中冠心病诊断标准相符合;患者每周心绞痛发作两次以上次数;排除药物过敏、不稳定型心绞痛、急性心肌梗死、肝肾功能异常、认知功能不全者;患者此次研究知情,签署了研究同意书;两组患者年龄、性别等资料利用统计学软件处理(P>0.05),可进行比较。