中药足浴治疗糖尿病合并冠心病患者的疗效及对APN、MBP、IGF-1的影响

范凤娟 张征宇

[摘要] 目的 分析中藥足浴治疗糖尿病合并冠心病患者的疗效及对APN、MBP、IGF-1的影响。 方法 选2018年2月至2020年2月间我院内分泌科收治的82例糖尿病合并冠心病患者作为研究对象，均分为两组（随机信封法），对照组41例选用常规治疗，观察组41例在对照组基础上选用中药足浴治疗，统计两组临床总有效率、临床指标、临床症状积分。 结果 观察组临床总有效率（92.68%）高于对照组（75.61%），差异有统计学意义（χ2=4.479，P<0.05）。观察组APN（8.91±1.82）mg/mL、IGF-1（4.94±0.91）pg/mL高于对照组APN（7.52±1.24）mg/mL、IGF-1（4.02±0.52）pg/mL，MBP（8.31±1.62）μg/mL、FPG（5.84±0.42）mmol/L低于对照组MBP（10.62±1.81）μg/mL、FPG（7.52±0.92）mmol/L，差异有统计学意义（P<0.05）。 观察组临床症状积分低于对照组，差异有统计学意义（P<0.05）。 结论 将中药足浴应用在糖尿病合并冠心病患者治疗中，可降低临床症状积分，改善临床指标，促进糖脂代谢，值得借鉴。

[关键词] 中药足浴;糖尿病;冠心病;APN;MBP;IGF-1

[中图分类号] R259          [文献标识码] B          [文章编号] 1673-9701（2021）25-0140-03

Efficacy of traditional Chinese medicine foot bath in the treatment of patients with diabetes and coronary heart disease and the influence on APN， MBP， and IGF-1

FAN Fengjuan   ZHANG Zhengyu

Fifth Ward， Lishui Chinese Medicine Hospital， Zhejiang Province， Lishui   323000， China

[Abstract] Objective To analyze the efficacy of traditional Chinese medicine foot bath in treating diabetic patients with coronary heart disease and the influence on APN， MBP， and IGF-1. Methods A total of 82 patients with diabetes and coronary heart disease admitted to the Department of Endocrinology in our hospital from February 2018 to February 2020 were selected as the research subjects. They were divided into two groups （random envelope method）. Forty-one cases in the control group received conventional treatment， and 41 cases in the observation group received the traditional Chinese medicine foot bath based on the treatment of the control group. The total clinical effective rate， clinical indicators， and clinical symptoms scores of the two groups were counted. Results The total clinical effective rate （92.68%） of the observation group was higher than that of the control group （75.61%），the difference was significant（χ2=4.479， P<0.05）. The APN（8.91±1.82） mg/ml， IGF-1（4.94±0.91） pg/mL of the observation group were higher than APN （7.52±1.24） mg/ml， IGF-1 （4.02±0.52） pg/mL of the control group. The MBP （8.31±1.62） μg/ml and FPG （5.84±0.42） mmol/L of the observation group were lower than MBP （10.62±1.81） μg/mL， FPG（7.52±0.92） mmol/L of the control group（P<0.05）. The clinical symptom score of the observation group was lower than that of the control group（P<0.05）. Conclusion The application of traditional Chinese medicine foot bath in the treatment of patients with diabetes and coronary heart disease can reduce clinical symptom scores， improve clinical indicators， and promote glucose and lipid metabolism， which is worth learning.