苓桂术甘汤联合温胆汤治疗痰湿壅盛型糖尿病的效果观察

梁艳彬

[摘要] 目的 探究苓桂术甘汤联合温胆汤治疗痰湿壅盛型糖尿病的临床效果。方法 选择2017年9月—2019年6月到该院就诊的52例痰湿壅盛型2型糖尿病为研究对象，根据治疗方案不同进行分组，对照组（n=26）采用常规西药治疗，观察组（n=26）在常规西药治疗的基础上应用苓桂术甘汤联合温膽汤治疗，对比两组血糖指标、中医证候积分以及不良反应发生情况。结果 两组干预前的空腹血糖、餐后2 h血糖、糖化血红蛋白水平差异无统计学意义（P>0.05），观察组患者干预后的上述血糖指标明显低于对照组（P<0.05）。经治疗后，观察组患者在肥胖、口渴不欲饮、肢体困重倦怠、舌苔厚腻方面的中医症候积分显著低于治疗前及对照组（P<0.05）。两组不良反应发生率比较，差异无统计学意义（P>0.05）。结论 苓桂术甘汤联合温胆汤治疗痰湿壅盛型糖尿病效果显著，可明显缓解临床症状，降低血糖，且其安全性较好。

[关键词] 糖尿病;痰湿壅盛型;苓桂术甘汤;温胆汤

[中图分类号] R587          [文献标识码] A          [文章编号] 1672-4062（2020）07（b）-0064-03

[Abstract] Objective To explore the clinical effect of Lingguishugan Decoction combined with Wendan Decoction in treating phlegm-dampness type diabetes. Methods A total of 52 patients with type 2 diabetes with phlegm， and dampness were selected as the research subjects from September 2017 to June 2019. The control group（n=26） was treated with conventional Western medicine and observation group（n=26） was treated with Lingguishugan decoction combined with Wendan decoction on the basis of conventional western medicine treatment， and the blood glucose index Tcm Sydromeinter and adverse reactions were compared between the two groups. Results There was no statistically significant difference in fasting blood glucose， blood glucose 2h after meals， and glycated hemoglobin levels before intervention between the two groups（P>0.05）. The above-mentioned blood glucose indexes of observation group after intervention were significantly lower than those of control group （P<0.05）. After treatment， the observation group's TCM symptom scores for obesity， thirst， unwillingness to drink， limbs tiredness， thick tongue coating was significantly lower than before treatment and control group（P<0.05）. The incidence of adverse reactions between the two groups was not statistically significant difference（P>0.05）. Conclusion Lingguishugan decoction combined with Wendan decoction is effective in treating phlegm-dampness type diabetes. It can obviously relieve clinical symptoms and lower blood glucose， and its safety is good.

[Key words] Diabetes; Phlegm-dampness type; Lingguishugan Decoction; Wendan Decoction

2型糖尿病是以慢性血糖水平升高为主要特征的代谢性疾病，其发生主要是由于机体胰岛素作用缺陷或分泌不足而引起的。近年，随着人们生活方式以及膳食结构的不断改变，该病发生率逐年升高，成为继心脑血管疾病、恶性肿瘤后第三大严重威胁人类身心健康的慢性非传染性疾病。当前临床往往予以常规西药进行治疗，以使患者的血糖水平控制到正常范围，降低急慢性糖尿病并发症发生风险，改善患者的生存质量。然而，单纯应用西药降糖，虽可在短时间内获得满意的疗效，但长时间用药有可能引起耐药性，再加上大多数糖尿病患者为老年人，长期用药不良反应发生风险高，故远期疗效并不理想[1]。现为探究中医药治疗2型糖尿病的有效性及安全性，该研究选取2017年9月—2019年6月收治的52例痰湿壅盛型2型糖尿病患者，根据中医辨证论治原则对痰湿壅盛型患者予以苓桂术甘汤和温胆汤治疗，具体报道如下。