探究宫腔镜子宫内膜微创术对患者生殖内分泌及子宫内膜容受性的影响

朱青娟

[摘要] 目的 探究宮腔镜子宫内膜微创术对患者生殖内分泌及子宫内膜容受性的影响。 方法 方便选取2016年1月—2018年12月在该院接受宫腔镜子宫内膜微创术治疗的82例患者作为研究对象，对其术前术后的生殖内分泌和子宫内膜容受性进行观察分析。结果 观察患者术前术后的生殖内分泌相关指标发现，术后的P（孕酮）（4.91±0.16）μg/L高于术前（4.30±0.24）μg/L，差异有统计学意义（t=5.980，P=0.000），术后E2（雌二醇）（230.98±17.03）ng/L高于术前（197.03±18.95）ng/L，差异有统计学意义（t=3.770，P=0.000），术后FSH（促卵泡激素）（9.12±0.33）IU/L高于术前（7.03±0.43）IU/L，差异有统计学意义（t=10.910，P=0.000），术后LH（血清促黄体生成素）（21.87±0.90）IU/L高于术前（17.99±0.87）IU/L，差异有统计学意义（t=8.770，P=0.000）。观察患者术前术后子宫内膜容受性相关指标发现，术后的子宫内膜厚度（13.01±0.76）mm较厚于术前（8.71±0.89）mm，差异有统计学意义（t=10.390，P=0.000），术后的PI（搏动指数）（0.81±0.04）低于术前（0.90±0.05），差异有统计学意义（t=4.420，P=0.000），术后RI（内膜动脉阻力指数）（2.21±0.13）低于术前（3.10±0.16），差异有统计学意义（t=12.210，P=0.000）。 结论 通过探究宫腔镜子宫内膜微创术对患者生殖内分泌及子宫内膜容受性的影响发现良好，可有效的对患者的生殖内分泌水平和子宫内膜容受性进行提升和改善，临床应用价值较高。

[关键词] 宫腔镜子宫内膜微创术;生殖内分泌;子宫内膜容受性

[Abstarct] Objective To explore the effect of hysteroscopic endometrial minimally invasive surgery on reproductive endocrine and endometrial receptivity. Methods Convenient select from January 2016 to December 2018， 82 patients who underwent hysteroscopic endometrial minimally invasive surgery in the hospital were enrolled as study subjects. The reproductive endocrine and endometrial receptivity before and after operation were observed and analyzed. Results  Observing the reproductive endocrine-related indicators of patients before and after operation， it was found that the postoperative P （progesterone）（4.91±0.16）μg/Lwas higher than that before surgery （4.30±0.24 ）μg/L，the difference was statistically significant （t=5.980， P=0.000）， postoperative E2 （estradiol） （230.98±17.03）ng/L is higher than preoperative （197.03±18.95）ng/L，the difference was statistically significant （t=3.770， P=0.000）， and FSH （follicle-stimulating hormone） （9.12±0.33） IU/Lwas higher than before surgery（7.03±0.43）IU/L，the difference was statistically significant（t=10.910， P=0.000）， postoperative LH （serum luteinizing hormone） （21.87±0.90） IU/Lwas higher than before surgery （17.99±0.87） IU/L，the difference was statistically significant（t=8.770，P=0.000）. Observing the related indexes of endometrial receptivity before and after the operation， the thickness of the endometrium after operation （13.01±0.76） mmwas thicker than that before operation （8.71±0.89） mm，the difference was statistically significant（t=10.390， P=0.000）， Postoperative PI （pulsation index） （0.81±0.04） was lower than preoperative （0.90±0.05），the difference was statistically significant（t=4.420， P=0.000）， postoperative RI （endometrial arterial resistance index） （2.21±0.13） was lower than before（3.10±0.16），the difference was statistically significant（t=12.210， P=0.000）. Conclusion By exploring the effect of endometrial minimally invasive hysteroscopy on the reproductive endocrine and endometrial receptivity of patients， we found that it is good， and can effectively improve the reproductive endocrine level and endometrial receptivity of patients. It has high clinical value.