王香
[摘要] 目的 探索地佐辛复合丙泊酚静脉麻醉在无痛胃镜检查中的应用效果及不良反应。方法 方便选取2018年1—12月期间该院实施无痛胃镜检查60例患者(实施奇偶数法分组模式),对照组的30例患者进行芬太尼麻醉,观察组的30例患者进行地佐辛复合丙泊酚静脉麻醉。 结果 观察组患者检查中VAS评分(0.53±0.19)分、检查中Ramsay镇静评分(3.99±0.27)分、拔除胃镜后立即VAS评分(1.95±0.56)分、拔除胃镜后立即Ramsay镇静评分(2.26±0.57)分、PaO2(96.88±9.63)mmHg、睁眼时间(5.65±1.86)min、睫毛反射消失时间(2.84±1.39)min、麻醉起效时间(4.92±1.37)min、丙泊酚用量(124.58±16.86)mg、不良反应(6.67%)均优于对照组,差异有统计学意义(t=1.529、1.188、2.432、2.137、51.398、5.623、4.153、4.266、56.325,χ2=11.624,P<0.05),同時观察组各时间段的MAP、HR稳定情况优于对照组,差异有统计学意义(P<0.05)。 结论 在实施无痛胃镜检查时,运用地佐辛复合丙泊酚静脉麻醉效果显著,且安全性更高。
[关键词] 地佐辛复合丙泊酚;静脉麻醉;无痛胃镜;不良反应
[中图分类号] R614 [文献标识码] A [文章编号] 1674-0742(2019)10(b)-0091-03
[Abstract] Objective To explore the application effect and adverse reactions of dextrozine combined with propofol intravenous anesthesia in painless gastroscopy. Methods From January to December 2018, convenient selected 60 patients with painless gastroscopy were performed in the hospital (the odd-even group method was implemented), and 30 patients in the control group underwent fentanyl anesthesia. 30 patients underwent intravenous anesthesia with dextrozine combined with propofol. Results In the observation group, the VAS score (0.53±0.19)points, the Ramsay sedation score (3.99±0.27)points, the VAS score (1.95±0.56)points after removal of the gastroscope, and the Ramsay sedation score (2.26±0.57)points immediately after removal of the gastroscope, PaO2(96.88±9.63)mmHg, blink time (5.65±1.86) min, eyelash reflex disappearance time (2.84±1.39) min, anesthesia onset time (4.92±1.37) min, propofol dosage (124.58±16.86) mg and adverse reactions (6.67%) were superior to the control group ,the difference was statistically significant(t=1.529, 1.188, 2.432, 2.137, 51.398, 5.623, 4.153, 4.266, 56.325, χ2=11.624, P<0.05), while observing the MAP of each time period of the group, the stability of HR was better than that of the control group ,the difference was statistically significant(P<0.05). Conclusion In the implementation of painless gastroscopy, intravenous anesthesia with dizocine combined with propofol is effective and safe.
[Key words] Dextrozine combined with propofol; Intravenous anesthesia; Painless gastroscopy; Adverse reactions
胃肠镜是目前诊断胃肠道疾病最常见的方法,早期由于技术有限,检查方式疼痛感较强,属于一种侵入性操作,导致患者难以接受、配合,出现躁动感,从而影响疾病判断[1]。而近年来,随着医疗技术和诊断技术的改进,无痛胃肠镜检查开始广泛推广,其可发挥一定镇痛、镇静功效,减轻胃肠镜引起的应激反应[2]。而为了达到更为有效、安全的镇痛效果,还可合理选择麻醉药,通过分析往期报道,可发现地佐辛复合丙泊酚效果更为显著,能够促使胃镜检查操作的更加顺利进行,提高机体耐受力,降低机体应激反应,发挥苏醒速度快、不良反应小、起效迅速等优势,获取满意镇痛效果[3]。该文在2018年1—12月期间方便选取60例实施无痛胃镜检查患者为试验对象,分别进行不同麻醉方案,报道如下。