探讨硫酸镁治疗小儿喘息性疾病的临床效果及安全性

赵树峰

[摘要] 目的 探討分析硫酸镁治疗小儿喘息性疾病的临床效果及安全性。方法 回顾性分析于2016年1月—2017年12月期间在该院治疗的小儿喘息性疾病患儿120例作为该次研究对象，按照患儿的不同治疗方法均分为两组，对照组和研究组患儿各60例。对照组患儿行常规治疗，研究组患儿则在常规治疗基础之上行硫酸镁治疗。对比分析两组患儿的临床治疗疗效以及各项观察指标和并发症发生率相较。 结果 通过对两组患儿行不同治疗方法，研究组患儿的临床治疗有效率相较对照组患儿明显较高，分别为95.00%与85.00%，两组差异有统计学意义（χ2=8.924，P<0.05）;研究组患儿的肺部湿啰音、喘息以及咳嗽等症状的消失时间，以及平时的住院时长相较对照组明显较短，两组差异有统计学意义（χ2=5.617，P<0.05）;且研究组患儿的临床并发症发生率相较对照组明显较少，分别为3.33%和10.00%，两组差异有统计学意义（χ2=5.617，P<0.05）。 结论 通过对小儿喘息性疾病患儿，行硫酸镁药物治疗可以取得显著的治疗疗效，且能够有效缩短患儿身体病症的存在时间，提升患儿的身体康复速率，药物起效时间相对较快，且无毒副作用减少患儿身体不良反应发生率，具有临床推广意义。

[关键词] 硫酸镁;小儿喘息性疾病;安全性

[中图分类号] R725.6          [文献标识码] A          [文章编号] 1674-0742（2019）05（a）-0112-03

[Abstract] Objective To analyze the clinical effect and safety of magnesium sulfate in the treatment of children with wheezing disease. Methods A retrospective analysis of 120 children with pediatric wheezing disease treated in our hospital from January 2016 to December 2017 was conducted. The treatment groups were divided into two groups according to the different treatment methods of the children， with 60 children in each group. The control group received routine treatment， and the study group was treated with conventional magnesium sulfate on the basis of conventional treatment. The clinical treatment efficacy of the two groups of children and the comparison of the observed indicators and the complication rate were compared. Results The clinical treatment efficiency of the children in the study group （95.00%） was significantly higher than that of the control group （85.00%）. There were statistically significant differences between the two groups （χ2=8.924， P<0.05）. The disappearance time of symptoms such as wetness， wheezing and cough in the lungs of the study group， and the usual length of hospitalization were significantly shorter than those in the control group， and there were statistically significant differences between the two groups （χ2=5.617， P<0.05）. The incidence of clinical complications in the study group （3.33%） was significantly lower than that in the control group （10.00%）. The difference between the two groups was statistically significant （χ2=5.617， P<0.05）. Conclusion Children with sexually transmitted diseases can achieve significant therapeutic effects by taking magnesium sulphate medication， which can effectively shorten the time of physical condition of the child， improve the rate of physical recovery of the child. And the drug has a relatively fast onset time without toxic side effects. The incidence of adverse reactions in children has clinical significance.