This biography will trace the growth of Wen Zhengming and explore how he became an artistic giant in an era that was illuminated by famous scholars and literati such as Shen Zhou, Zhu Yunming, Tang Yin, and Wang Shizhen. It will also pay attention to the relationship between Wen Zhengming, the city of Suzhou, and the people of different social classes in the city, and discuss the influence of Suzhou in the 15th and 16th centuries on Wen Zhengming and the mark that Wen Zhengming left on Suzhou in the 16th century and beyond.