Value of preoperative erythrocyte sedimentation rate, CRP and D-D levels in evaluating the prognosis of elderly patients after hip replacement

Yong Yao, Jian-Xin Yan, Gang Wu

Joint surgery, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, 445000, Hubei, China

ARTICLE INFO

Article history:Received 12 Dec 2019 Received in revised form 22 Dec 2019 Accepted 3 Jan 2020 Available online 14 Jan 2020

Keywords:erythrocyte sedimentation rate C-reactive protein D-dimer hip replacement predictive value

ABSTRACT Objective: To analyze the clinical value of blood sedimentation rate, C-reactive protein (CRP) and D-dimer (D-D) expression levels in elderly patients before hip replacement for judging the prognosis after operation. Methods 88 patients who needed hip replacement in orthopaedic surgery of our hospital from January 2014 to December 2017 were selected as the research object. According to the prognosis of patients, they were divided into two groups. 42 patients with good prognosis were treated as observation group and 46 patients with poor prognosis were treated as control group. The ESR and CRP of the two groups were recorded and analyzed before and after operation. The expression level of D-D, perioperative changes, and the prognostic value of the area under the curve (AUC) were compared by drawing the patient's working characteristic curve (ROC curve). Results The expression levels of ESR, CRP and D-D in the observation group were significantly higher than those in the control group (P ＜ 0.05). The expression levels of CRP in the observation group were significantly higher than those in the control group (P ＜ 0.05). The expression levels of ESR and CRP in the observation group before discharge were significantly higher than those in the control group (P ＜ 0.05). There was significant difference between the two groups (P ＜ 0.05); the level of ESR expression before and 2 days after operation was significantly lower than that before discharge (P ＜ 0.05); the level of ESR expression before operation was significantly lower than that 2 days after operation (P ＜ 0.05); and the CRP and D-D table before operation were compared between the two groups (P ＜ 0.05). The level of CRP and D-D expression in two groups was significantly higher than that before discharge (P ＜ 0.05). In this study, two groups of patients were infected. The incidence of thrombosis in the observation group was higher than that in the control group, but the difference was not statistically significant (P ＞ 0.05). The Harris score of the observation group was significantly higher than that of the control group (P ＜ 0.05). Conclusion There are abnormal levels of ESR, CRP and D-D expression in elderly patients with hip replacement before operation, and they have certain clinical value in evaluating the prognosis of elderly patients after hip replacement.

✉Corresponding author: Jian-Xin Yan, Central Hospital of Enshi Tujia and Miao Autonomous Prefecture.

E-mail: 3228391827@qq.com.