胆源性消化不良患者采取复方阿嗪米特肠溶片治疗的效果分析

嵇秀丽

【摘要】 目的 探讨复方阿嗪米特肠溶片治疗胆源性消化不良的临床效果。方法 60例胆源性消化不良患者， 按照随机数字法分为对照组和观察组， 每组30例。对照组患者采用消炎利胆片治疗， 观察组患者采用复方阿嗪米特肠溶片治疗。比较两组患者临床症状改善时间、治疗后胃肠症状评估量表（GSRS）评分以及不良反应发生率。结果 观察组患者腹胀、恶心、呕吐症状改善时间分别为（12.32±

3.39）、（7.64±1.37）、（7.23±2.36）d均明显短于对照组的（14.28±3.69）、（8.36±1.15）、（8.44±1.54）d， 差异具有统计学意义（P<0.05）。治疗后， 观察组患者GSRS评分均明显低于对照组， 差异具有统计学意义（P<0.05）。观察组患者不良反应发生率为6.67%， 明显低于对照组的26.67%， 差异具有统计学意义（P<0.05）。结论 复方阿嗪米特肠溶片治疗胆源性消化不良效果较好， 可有效改善患者临床症状， 降低不良反应发生率， 提高患者生活质量， 值得临床推广应用。

【关键词】 复方阿嗪米特肠溶片；胆源性消化不良；消炎利胆片

DOI：10.14163/j.cnki.11-5547/r.2018.14.007

Analysis of effect of compound azintamide enteric-coated tablets in the treatment of patients with biliary dyspepsia JI Xiu-li. Inner Mongolia Hulunbeier Peoples Hospital， Hulunbeier 021008， China

【Abstract】 Objective To discuss the clinical effect of compound azintamide enteric-coated tablets in the treatment of patients with biliary dyspepsia. Methods A total of 60 patients with biliary dyspepsia were divided by random number table method into control group and observation group， with 30 cases in each group. The control group was treated with inflammation-resolving gall-bladder-excreting tablet， and the observation group was treated with compound azintamide enteric-coated tablets. Comparison were made on clinical symptom improvement time， gastrointestinal symptom rating scale （GSRS） score and incidence of adverse reactions between the two groups. Results The observation group obviously shorter abdominal distension， nausea， vomiting symptoms improvement time as （12.32±3.39）， （7.64±1.37） and （7.23±2.36） d than （14.28±3.69）， （8.36±1.15） and （8.44±1.54） d in control group， and the difference was statistically significant （P<0.05）. After treatment， the observation group had obviously lower GSRS score than the control group， and the difference was statistically significant （P<0.05）. After treatment， the observation group had obviously lower incidence of adverser reactions as 6.67% than 26.67% in the control group， and the difference was statistically significant （P<0.05）. Conclusion Compound azintamide enteric-coated tablets shows excellent effect in treating biliary dyspepsia， and it can effectively improve the clinical symptom，

reduce incidence of adverse reactions， and improve the quality of life. It is worthy of clinical promotion and application.

【Key words】 Compound azintamide enteric-coated tablets； Biliary dyspepsia； Inflammation-resolving gall-bladder-excreting tablet

膽源性消化不良是消化内科常见的疾病类型， 主要是由多种胆道疾病所导致的胆汁储存、浓缩以及排出出现障碍， 致使胆汁量明显不足， 消化酶分泌不断减少且活性不断下降所引起的器质性消化不良[1]。患者一般会出现食欲不振、早饱、食后腹胀、腹部疼痛、嗳气以及腹泻等症状， 并且无明显怕冷、畏寒以及发热现象发生， 其发生多与人们的生活习惯以及饮食习惯变化有关， 发病率较高且呈现出逐年上升的趋势， 对患者的身心健康以及日常生活均有严重影响， 需要及时采取有效治疗来改善患者预后， 提高生活质量[2]。临床一般采用药物治疗， 复方阿嗪米特肠溶片治疗胆源性消化不良效果较好且不良反应较少， 可促进患者症状快速缓解[3]。本次研究主要探讨复方阿嗪米特肠溶片治疗胆源性消化不良的临床效果， 现报告如下。