KEYWORD INDEX (2018, Volume 34)

(+)2-(1-Hydroxy-4-oxocyclohexyl)ethyl caffeate 2247

1-Methyl-4-phenylpyridinium 1061

2,4,6-Trinito-benzene-sulfonic acid 1082

2-Arachidonoylglycerol 1345

3,4-Dihydroxyacetophenone 1856

3’-untranslated region 1229

3-Phosphoinositide-dependent protein-1 225

4-Phenylbutyric acid 2215

5-Aza-2’-deoxycytidine 52

5-Fluorouracil 152 206

5-Hydroxytryptamine 825

10-Gingerol 2166

20-Hydroxyeicosatetraenoic acid 2294

Abietic acid 1377

ACE2-Ang(1-7)-MAS axis 36

Acetyl cholinesterase 1056

Achilles tendonitis 1884

Acid sphingomyelinase 1207

Acinetobacter baumannii 2267

Acteoside 102 1633

Actin 2080

Activator protein-1 905

Acute carbon monoxide poisoning 2203

Acute ischemic stroke 1805

Acute kidney injury 681 1239 1679

Acute liver injury 1661

Acute lung injury 188

Acute myeloid leukemia 375 1115 1134

Acute myocardial infarction 1935

Adaptive thermogenesis 1827

Adeno-associated virus type 9 2101

Adenosine 1706

Adenosine triphosphate binding cassette transporter A1 2127

Adhesion ability 945

Adhesion molecule 1558

Adipogenic differentiation 918

Adiponectin 1396

Adiponectin receptor 1 1396

Adipophilin 1189

Adipose-derived stem cells 1884

Adra1dgere 1306

Adriamycin 638

Advanced glycation end products 1711

Advanced glycosylation end products 1377

Aging mice 562

Agkistrodon acutus snake venom protein C activator 905

AGR2 gene 1690

Airway inflammation 516 1102

Akt signaling pathway 1435

Akt/GSK-3β/Snail signaling pathway 1124

AKT/HIF-1α/VEGF signaling pathway 48

Akt/mTOR/p70S6K signaling pathway 2267

AKT1 1443

AKT3 gene 2160

Alcoholic live diseases 1095 1310

Allergic asthma 1553

All-transretinoic acid 724 1730

Aloperine 281

Alpha-lipoic acid 1844

Alzheimer disease 95 168 294 1056 1154 1354 2215

AML1-ETO fusion protein 1598

AMP-activated protein kinases 1196 1856

AMPK signaling pathway 2186

Amyloid β-protein 1056 1354 1805

Angiogenesis 48 644 651 1002 1147

Angiopoietin-2 41

Angiotensin (1-7) 893 1963

Angiotensin Ⅱ 840 893 1183 2101

Angiotensin Ⅱ type 1 receptor 840

Angiotensin Ⅱ type 1 receptor autoantibody 474

Angiotensin-converting enzyme 147

Annulus fibrosus 1877

Anoxia 1941 1953

Anthocyanins 2278

Antisperm antibody 1497

Aorta rings 1779

Apelin 1513

Aplastic anemia 687

ApoE-/-mice 2278

Apoptosis 30 64 87 102 130 168 206 212 218 225 239 245 288 294 315 435 447 452 458 474 539 562 624 631 638 657 706 717 764 770 804 858 893 976 986 1020 1025 1037 1042 1050 1067 1076 1120 1177 1183 1214 1223 1233 1239 1257 1264 1369 1377 1404 1449 1461 1478 1571 1587 1616 1679 1690 1711 1715 1730 1737 1790 1796 1821 1861 1922 1941 1969 1976 1982 2012 2049 2085 2091 2101 2133 2154 2180 2186 2193

Apoptotic bodies 358

Apoptotic protease-activating factor-1 1610 2193

APP/PS1 mice 1050

Aquaporin 4 1363 1805

Arachidonic acid 2247

Arachidonylethanolamide 1538

Arhythmia 996

Arteriosclerosis 2278

Artesunate 64

Aspirin 1492

Asthma 353 516

Astragaloside 2121

Astragaloside IV 644 2038

Astragalus polysaccharides 1196 1877

Astrocytes 566 862

Asymmetric dimethylarginine 1415

Atherosclerosis 2 393 724 846 1189 1553 2032 2121

ATM signaling pathway 1990

Atorvastatin 846

ATP binding cassette transporter A1 2121

Aurora protein kinase inhibitor 945

Autophagy 464 474 521 956 1020 1277 1369 1377 1455 1527 1532 1593 1706 1895 1963 2038 2055 2074 2139 2267

AZD8055 1020

Bacillus Calmette-Guérin 516

BAG2 gene 428

Baicalein 417 900

Baicalin 1571

Baroreflex sensitivity 36

Basal core promoter region 1684

Basic fibroblast growth factor 48

Basilar arterial smooth muscle cells 989

B-cell lymphoma/leukemia 11B 1229

B-cell phenotype 52

Bcl-xL 206

BDNF-TrkB signaling pathway 1633

Beclin-1 399

Beige fat cells 1827

Berberine 1025

Berberine hydrochloride 1870

BG4 2091

BGC-823 cells 206

Bilberry anthocyanins 1291

Bioinformatic analysis 664

Biomechanics 1884

Bladder cancer 58 239 1025

Blood glucose 2

Blood lipids 2 270

Blood-brain barrier 1363 1796

BMP signaling pathway 544

Bone marrow mesenchymal stem cells 308 862 918 1409 2113

Bone marrow stromal cells 599 2256

BRAF protein 2166

Brain edema 1363

Brain microvascular endothelial cells 1796

Brain natriuretic peptide 265

Brain-derived neurotrophic factor 699

Breast cancer 81 218 930 1009 1032 1245 1443 1603 1900 2097 2186 2198

Brilliant blue G 2203

Bronchial asthma 163

Bronchial epithelial cells 1329

Burkitt lymphoma 1508

BV-2 cells 1486

C/EBP homologous protein 1369 1922

c1orf109 gene 141

Ca2+handling 489

Ca2+/calmodulin-dependent protein kinase Ⅱ 1404

Ca2+/CaM signal pathway 651

Calcium channel 825 1779

Calcium ion 1306

Calmodulin 1306

Calpain-2 1821

Calreticulin 926

Cancer stem cells 549

Cancer vaccines 618

Captopril 1501

Carcinoembryonic antigen-related cell adhesion molecular 1 1737

Cardiac function 10 277 1538 1565

Cardiac stem cells 961

Cardiac systolic and diastolic functions 1547

Cardiomyocytes 281 2101

Cardiorenal syndrome 265

Cardiotoxicity 2133

Cardiovascular diseases 2294

Carnosine 1565

Caspase-3 2193

Caspase-12 1821 1922

Caspases 168

Caudate nucleus 1345

CBir1 flagellin 534

CCAAT/enhancer-binding protein homologous protein 315

CCN1 188

CD4+T cells 1661

CD44 549

CEBPAgene 1598

Cell adhesion 2256

Cell cycle 212 606 800 1616

Cell cycle arrest 1025

Cell differentiation 961 1666

Cell growth 578 1233

Cell invasion 70 926 1037 1455 1492 1579 2012

Cell isolation 380

Cell migration 70 200 232 410 417 458 578 586 778 793 833 926 961 1435 1443 1743 1990 1997 2004

Cell proliferation 200 417 428 458 464 586 593 624 770 812 833 961 1390 1435 1478 1603 1848 2004 2146 2173

Cell reprogramming 1409

Cell viability 87 225 245 410 651 706 778 793 804 820 930 976 989 1120 1245 1257 1264 1427 1492 1982 2166 2180

Central memory CD8+T cells 1666

Central nervous system 36

Central serous chorioretinopathy 1110

Cepharanthine 1587

Ceramide 1207

Cerebral infarction 1715 2038

Cerebral ischemia 2018

Cerebral ischemia-reperfusion injury 956

Cerebral ischemic stroke 2032

Cerebrovascular diseases 760

Cervical cancer 631 804 1120 1990

Cervical spondylosis 1877

Checkpoint kinase 1 200

Chelerythrine 1324

Chemokine CCL3 301

Chemokine CXCL1 308

Chemosensitivity 2154

Chemotherapy resistance 1042

Cholangiocarcinoma 1020

Chondrocyte 2074

Choroidal neovascularization 1110

Chronic cerebral hypoperfusion 1171

Chronic cerebral ischemia 913

Chronic heart failure 277 385 983 1501 1538

Chronic hepatitis B 1684

Chronic liver diseases 358

Chronic myeloid leukemia 375

Chronic obstructive pulmonary disease 188 315 1102 1697

Chronic pancreatitis 329

Chronic unpredictable mild stress 1633

Chrysophanol 1354

Cigarette smoke extract 1329

circRNAs 760

Circularly permuted yellow fluorescent protein 1649

Cisplatin 218 447 539 1610 1616 1679

c-Jun 206

Cladribine 606

ClC-3 335

Clear cell renal cell carcinoma 178

Cleft palate 1638

Clonidine 913

c-Met signaling pathway 470

Cobalt chloride 717

Cocaine- and amphetamine-regulated transcript 1363

Cognition 1354

Cognition disorder 878 1171

Cognitive function 1154

Cognitive impairment 562

Co-immunoprecipitation 1270

Colitis 534 1090

Collagen type I 1014 1291

Collagen type IV 124

Collagen-induced arthritis 2247

Colon cancer 75

Colorectal cancer 152 245 2154

Compensation 1547

Congenital heart disease 950

Connective tissue growth factor 1142 1672 2290

Connexin 43 41 1565 2074

Copeptin 265

Cordycepin 1435

Coronary arteries 825

Coronary artery bypass graft surgery 1383

Coronary atherosclerotic heart disease 1214

Corticosterone 693

CRISPR/Cas9 technique 2173

Curcumin 168 322

CXC chemokine receptor 4 1264

Cyclin D1 1982

Cyclins 428

Cyclo-oxygenase 2 556 2283

Cyclosporin A 1770

Cystine nephropathy 754

Cytokeratin 2080

Cytokines 606 1469 1661

Cytotoxic T-lymphocytes 612 618 934

Death receptor 5 81 212

Definitive endoderm 1812

Dehydroepiandrosterone 724 1905

Dendritic cells 612

Dendritic spines 2210 2215

Depression 102 699 870 1633

Development 950

Dexmedetomidine 681

Dextromethorphan 870

DHCR24 1333

Diabetes 482

Diabetes mellitus 1396

Diabetic cardiomyopathy 10 14 764 489 969 1207 1421 1565 1947 2271

Diabetic cutaneous ulcers 2106

Diabetic hepatopathy 556

Diabetic kidney disease 754

Diabetic liver injury 712

Diabetic nephropathy 23 494 940 1571 1835 1844 1953 1969 2234

Differential expression 75

Differentiation 1730 1812

Diffuse large B-cell lymphoma 1508

Dihydromyricetin 1610

Diminazene aceturate 147

Dithiothreitol 1821

DL-3-n-butylphthalidle 1002

DNA methylation 178 1638

DNA methyltransferases 178

DNA-binding protein 1672

DNA-damage-inducible transcript 4 956

Doxorubicin 435 2133

Drug resistance 152 218 470 549

Early brain injury 288

Early prediction 265

Edaravone 1805

Electroacupuncture 1171

Embryonic development 1067

Endometrial carcinoma 1587

Endophilin A2 2139

Endoplasmic reticulum stress 102 315 857 1239 1377 1690 1790 1821 1922 2215

Endothelial cell 1914

Endothelial damage 735

Endothelial nitric oxide synthase 840

Endothelial progenitor cells 1427

Endothelial-mesenchymal transition 508 1724 1935

Endothelin receptor A 878

Endothelin-1 878 1697 1929

Energy metabolism 1827

Enhancer ofzestehomolog 2 1449 1461

Enrichment analysis 1638

Eosinophils 1383

Epigallocatechin gallate 1895

Epigenetic modification 1598

Epigenetics 52

Epithelial ovarian cancer 549

Epithelial-mesenchymal transition 70 423 926 1009 1250 1579 1622 1124 1748 1910 2004

Epitopes 441

ERK signaling pathway 913 2234

ERK/P53 signaling pathway 1042

ERK1/2 sigaling pathway 1435 1742

Erythrocyte deformability 130

Erythrocyte osmotic fragility 130

Erythropoietin 1067

Esophageal cancer 800

Estrogen 364

Estrogen receptor 1742

Ethyl acetate extract ofPleionebulbocodioides(Franch.) Rolfe 770

Eukaryotic initiation factor 4E 1587

Evodiamine 212

Exercise intervention 745

Exercise training 36

Exosomes 10 572 301 358 717 862 2113

Expression pattern 544

Extracellular matrix 173 1877 1914

Extracellular signal-regulated kinases

Extracellular vesicles 358

Fasudil 1154

Fatty acid translocase 393

Fatty-acid amide hydrolase 385

F-box/WD repeat containing protein 7 2271

Fc ε receptor I 1553

Female infertility 1497

Fibroblast growth factor-21 2228

Fibroblasts 2222

Fibrosarcoma 447

Fibrosis 173 1277

Filamin-A 2210

Fimasartan 1421

FIZZ1 1102

Flagellin 1082

Flavonoids from stem and leaf ofScutellariabaicalonsisGeorgi 95

Flora imbalance 885

Flow cytometry 2301

FLT3-ITD 1115

Fluorocitrate 2018

Follicle stimulating hormone receptor 380

FOXO1-Bim/Noxa signaling pathway 1610

Free radicals 1649

Frizzeld-2 protein 2240

Fufang Zhenzhu Tiaozhi capsule 270

Fusion protein 1754

Gallbladder cancer 1435

Gastric cancer 410 417 778 1748 1976 1982 1997 2091 2146

Gastric carcinoma 1037

Ge Xia Zhu Yu decoction 159

Gefitinib 470

Gene 1115

Gene expression regulation 1134

Gene regulation 786

Genetic polymorphisms 137 1890

Genistein 1895

Genome editing 2173

Ginsenoside Rh1 163 706 1763 2290

Ginsenoside RH2 113

Glioma 200 566 624 1449

Glomerular filtration rate 1415

Glomerular mesangial cells 30 494

Glucocorticoid receptor 353

Glucocorticoids 1666

Glucose transporter 2 194

Glucose-regulated protein 78 858 1922

Glucose-sensitive neurons 1163

Glutamic acid 1532

Glutaredoxin 1 2256

G-protein-coupled receptor 75 2294

G-quadruplex 2091

Granulosa cells 1711

Growth arrest-specific homeobox protein 989

GSK-3β/Snail signaling pathway 1009

GST-pulldown test 1270

Guangxi population 137

H9c2 cells 1404 1941

Heart 950

Heart failure 1785

Heart function 147

Heat shock protein 22 846

Hemeoxygenase-1 681

Hemoglobin oxygen dissociation curve 130

Hemorrhagic shock 364 681

Hepatic fibrosis 1324 1895

Hepatic oval cells 194

Hepatic steatosis 521

Hepatic stellate cells 1895

Hepatitis B vaccine 516

Hepatitis C virus 1333

Hepatocellular carcinoma 64 578 618 812 945 1706 2193

Hepatocellular steatosis 2

Hepatocyte growth factor 470 1622

Hepatocytes 118 1856

HepG2 cells 1317

HIF-1α/iNOS signaling pathway 2018

HIF-1α/VEGF signaling pathway 2049

High glucose 16 259

High-fat diet 764 1720

High-mobility group box protein 1 404 672 1711

HIPK2 gene 1076

Hippocampal neurons 699

Hippocampus 740 2203 2210

Histone deacetylase 1 23 452

Histone H3 950

Histone modification 178

HLA-A2-restricted peptides 441

HLA-A3 934

Hodgkin lymphoma 52

Homocysteine 1196

Hormone 1333

Huangjiao granule 1715

Human bone marrow mesenchymal stem cells 301

Human cumulus cells 380

Human cytomegalovirus 1270

Human dermal microvascular endothelial cells 657

Human embryonic lung fibroblasts 1672

Human epidermal growth factor receptor 2 2198

Human fetal scleral fibroblasts 1291

Human glomerular endothelial cells 893

Human induced pluripotent stem cells 1812

Human lumbar nucleus pulposus cells 706

Human mural granulosa cells 380

Human T-lymphotrophic virus 1 2261

Human umbilical vein endothelial cells 10 16 259 606 905 1763 724

Hydrogen molecule 30 1369

Hydrogen peroxide 918

Hydrogen sulfide 118 259 1277

Hydroxyproline 1324

Hyperbaric oxygen 2049

Hyperhomocysteinemia 2026

Hyperlipidemia 2278

Hypertension 252 878 1142 1415 2294

Hyperthyroid heart disease 996

Hypobaric hypoxia exposure 2210

Hypothalamic paraventricular nucleus 1163

Hypoxia 41 130 657 1002 1076 1547

Hypoxia/reoxygenation 857 1214

Hypoxia/reoxygenation injury 1404

Hypoxia-hypercapnia pulmonary hypertension 508

Hypoxia-inducible factor-1α 1201 1737

Hypoxic pulmonary hypertension 501

Hypoxic-ischemic encephalopathy 740 1177

IKKs/NF-κB signaling pathway 1329

Immunglobulin E 1553

Immunophenotype 2301

Immunosuppression 108

Immunotherapy 1666

Imperatorin 81

Invitroculture 380

Invivoimmunogenicity 441

Inducible nitric oxide synthase 556 1297

Inflammation 147 281 393 404 482 494 846 1095 1201 1486 1697 2032

Inflammatory bowel disease 1082 1090

Inflammatory cytokines 2062

Inflammatory factors 163 270

Inflammatory mediators 353

Inflammatory pain 340

Inflammatory responses 528 2026 2228

Influenza A virus 2062

INS-1 cells 474

Insulin resistance 2 1317 1720

Insulin-like growth factor 2 578

Insulin-like growth factor 2 mRNA-binding protein 1 1848

Intercellular adhesion molecule-1 724

Interferons 2261

Interferon-γ 1653

Interleukin-1 receptor-associated kinase-1 1947

Interleukin-1β 1284 1297 1301 1935

Interleukin-4 1102

Interleukin-6 308 1171 1508 1702

Interleukin-8 2234

Interleukin-9 1748

Interleukin-17 885

Interleukin-17A 2127

Interleukin-22 137 940 1301

Interleukin-23 885

Interleukin-27 1090

Interstitial cells of Cajal 1532

Intervertebral disc 1877

Intrinsic mitochondrial apoptosis pathway 770

Inwardly rectifying potassium channels 1183

Ionizing radiation 1250

Irbesartan 521

Ischemia 1002

Ischemia-reperfusion injury 281 1363 1396 1715 1702 1790 1805 2038 2055 2044 2049

Ischemic postconditioning 2018

Ischemic preconditioning 1396

Isoflurane 562

Isoprenaline 2139

Itchgene 1317

Jagged1 1233

JAK/STAT signaling pathway 58

JAK2/STAT3 signaling pathway 1076 1171 1715

Juglone 1910

Kaempferol-3-O-rutinoside 833

Kaposi sarcoma-associated herpesvirus 2085

KDM5B gene 2198

Keap1/Nrf2 signaling pathway 113

Ketamine 1628

Ketotifen 534

Kidney 1067

Krüppel-like factor 4 2154

Krüppel-like factor 15 672

Krüppel-like factor 17 786

Ku70 protein 2261

Kunming mice 329

L-arginine 329

L-ARG-NO-cGMP signaling pathways 870

L-carnitine 1953

Left ventricular ejection fraction 1785

Leonurine 1929

Leptomycin B 1603

Leucine-rich repeat kinase 2 528

Leukemia 87 770

L-glutamine 1720

Lipid accumulation 1189 2127

Lipid metabolism 2121

Lipidosis 1129

Lipids 137

Lipopolysaccharides 118 308 534 693 735 1345 1486 1558 1653

Lipotoxicity 2240

Liraglutide 2026

Liver 1702

lncLSTR 1129

Long non-coding RNA 75 593 820

Long non-coding RNA MALAT1 2146

Long non-coding RNA PCAT1 2004

Long non-coding RNA PVT1 232

Long peptide 2283

L-type voltage-gated calcium channels 1345

Lung 2055

Lung adenocarcinama 612 786 1042

Lung cancer 1 188 225 423 428 458 464 599 1014 1124 1264 1622 1690 1742 2283

Lung injury 124

Lung tissue 163

Lutein 930

Lycium barbarum polysaccharides 976

Lysine specific demethylase 1 1812

Macrophages 528 1369 1553 1653 1861

MAGEC2 618 934

Malignant phenotypes 1257

Malignant transformation 194

Mammalian target of rapamycin 1706

Mammary hyperplasia 544

MAPK signaling pathway 2 900 2012 2106

MAPK/ERK signaling pathway 599 687

Marsdeniatenacissimaextract 2180

Mas receptor 893

Mast cell degranulation 1082

Maternal expressed gene 3 1706

Matrix metalloproteinase 2 1291

Matrix metalloproteinase-9 124

Matrix metalloproteinases 804 1770 1805 1877 1914

MCF-3 cells 2097

Mcl-1 gene 1861

Mechanical stress 2074

Melanoma 2166 2180

Mesenchymal stem cells 2080

Metastasis 1579

Metformin 159 2186

Methylation 950

MethylRAD-Seq 1638

Microalbuminuria 940

Microbubbles 358

Microcirculation 1914

MicroRNA-1 1929

MicroRNA-7 1661

MicroRNA-7-5p 1317

MicroRNA-21 729 961 1785 1844

MicroRNA-24 1042

MicroRNA-25 1214

MicroRNA-29a 1257

MicroRNA-29b 1997

MicroRNA-30c 804

MicroRNA-33a 2121

MicroRNA-34a 1455 1884

MicroRNA-92b 1997

MicroRNA-103b 664

MicroRNA-106a 1032

MicroRNA-106b 1997

MicroRNA-125a-5p 1009

MicroRNA-126 1461

MicroRNA-126-5p 638

MicroRNA-130a 989

MicroRNA-133a 1142

MicroRNA-141 1245 1571

MicroRNA-145 631

MicroRNA-146 1947

MicroRNA-146a 1702

MicroRNA-153 58

MicroRNA-195 458

MicroRNA-196b 152

MicroRNA-215 1587

MicroRNA-326 1982

MicroRNA-339 1848

MicroRNA-381-3p 699

MicroRNA-451 494

MicroRNA-497 2160

MicroRNA-502-5p 1284

MicroRNA-551 232

MicroRNA-570-3p 2146

MicroRNA-1246 1990

MicroRNAs 178 760 1229 1527

Microtubule-associated protein 1 light chain 3 1532

Middle cerebral artery occlusion 113

Migration ability 945

Min6 cells 1963

Mineralization 1870

Minocycline hydrochloride 909

miR-483-5p 578

Mitochondria associated encloplasmic reticulum membranes 539

Mitochondrial membrane potential 294 1478

Mitochondrial oxidative stress 16

Mitomycin C 1025

Molecular simulations 2166

Monoamine neurotransmitters 1633

Monocrotaline 900

Monocyte chemoattractant protein-1 346

Morinda officinalis oligosaccharides 857

Motor symptoms 745

Mouse model 764

Mucin 2 534

Mucin 4 441

Multiple myeloma 375 1233

Multiple organ dysfunction syndrome 124

Muscarinic receptor 3 423

Mutation 1229 1684

MYBgene 458

Myc-associated zinc-finger protein 141

Mycobacterium tuberculosis 528 1861

Myeloid-derived suppressor cells 108

Myeloperoxidase 399

Myocardial fibrosis 48 1142 1183 1501 1770 1929

Myocardial hypertrophy 2139

Myocardial infarction 48 404 644

Myocardial infarction-associated transcript 593

Myocardial injury 638

Myocardial ischemia 399

Myocardial ischemia-reperfusion injury 1201

Myocardin 1409

Myoendothelial gap junctions 41

Myofibroblasts 2222

Naïve T cell 1301

Na+/dicarboxylate contransport 1 2068

NADPH oxidase-4 1014

NANOG 549

Nanoparticle tracking analysis 301

N-arachidonoylethandamide 385

Nasopharyngeal carcinoma 926 1250 1579 2173

NB4 cells 1730

NCM460 cells 729

Necroptosis 1649

Neoplasm invasion 232 245 793 820 1009 1032

Neovascularization 113

Nerve cells 1050

Nerve regeneration 1154

Neural stem cells 566 717

Neuregulin-1β 1501

Neuronal nuclear antigen 1905

Neurons 566 717 1177

Neuroprotection 572

Neuroregeneration 1527

Neurotherapy 572

Neurotransmitters 983

Neutrophils 2256

NFATc1 protein 1835

NF-κB 270 1558

NF-κB signaling pathway 340 930 1311 1339 2154

NF-κB/TLR4 signaling pathway 2032

Nifedipine 1779

Nitric oxide 1297

Nitroglycerin 1427

NLRP3 inflammasome 118 1090 1935

N-methyl-D-aspartate 870

N-Myc interactor 1270

Nobiletin 1129

Nodosin 2193

Nonalcoholic fatty liver disease 1129

Non-Hodgkin lymphoma 52

Non-small-cell lung carcinoma 586 593 1301

No-reflow phenomenon 399

Norepinephrine 735 1415

Notch signaling pathway 245 308 2032

Notch1/Dll4 signaling pathway 1002

NPY receptor signaling pathway 1163

NRE-52E cells 2068

Nrf2 signaling pathway 30

Nrf2/ARE signaling pathways 1245

Nrf2/HO-1 signaling pathway 1061 1223

Nuclear factor E2-related factor 2 1329 2228

Nuclear factor-κB 70 159 322 556 672 681 905 1953 2101

Nuclear localization 1603

Nuclear translocation 1443

Nucleotide-binding oligomerization domain-like receptor protein 3 693

Nude mice 786

Obesity 1163 1497 1720

Obstructive renal injury 1277

Occludin 729

Okadaic acid 95

Oligodendrocyte progenitor cells 566

Optical coherence tomography 1110

Oral squamous cell carcinoma 1737 2004

Orexin-A 1163

Organ fibrosis 1518

Organ injury 364

Osteoarthritis 1284 2074

Osteoblast differentiation 1870

Osteoporosis 1870

Osteosarcoma 820 1455 2012

Osthole 435

Outer membrane protein A 2267

Outer retinal structure 1110

Ovarian cancer 70 232 539 793 1616

Oxidative damage 1941

Oxidative stress 30 113 252 482 501 918 976 1061 1095 1196 1223 1354 1513 1565 1697 2026 2133 2228

Oxidized low-density lipoprotein 1369

Oxygen-glucose deprivation 1796

Oxytocin 740

P21 1239

p38 MAPK signaling pathway 1679 2026

p38 mitogen-activated protein kinase 1929

Paclitaxel 2186

Paeoniflorin 1050

Paired helical filaments 95

Paired-related homeobox 2 410

Palmitic acid 393 1129 1963 2240

Panaxadiol saponins 687

Pancreatic cancer cells 1593

Papillary thyroid cancer 2160

Paraventricular nucleus 385 1538

Paraventricular nucleus of hypothalamus 983

Parkinson disease 108 745 1628

Parkinson disease protein 7 1061

Patch-clamp techniques 740

Pathogenesis 1518

Peginterferon α-2b 1684

Penthorum chinense Pursh 1095

Perfluorooctanoic acid 353

Periodontal pathogens 909

Peripheral nerves 1527

PERK/eIF2α signaling pathway 315

Peroxisome proliferator-activated receptor-γ coactivator-1α 712 1207 1827

PGRNgene 586

Phosphatase and tensin homolog deleted on chromosome 10 1941

Phosphatase of regenerating liver-3 375

Phosphoglycerate kinase 1 1138

Phospholamban 1404

PI3K/Akt signaling pathway 281 423 624 1014 1050 1189 1250 1870 1976 2106 2222

PI3K/Akt/eNOS signaling pathway 976 1427 2062

PI3K/Akt/mTOR signaling pathway 521 1593 2180

PKC/Rho kinase signaling pathway 825

PKD1-HDAC5-VEGF signaling pathway 644

Plasminogen activator inhibitor 1 1763

Plateau 130

Platelet inhibitor fromAgkistrodonhalysvenom 1558

Pneumonia 1383

Podocytes 1835

Poly(ADP-ribose) polymerase-1 218

Polycystic ovary syndrome 159 1497 1711

Positive regulatory domain zinc finger protein 2 58

Postsynaptic density 2044

Postsynaptic density protein-95 1905

Post-transcription regulation 760

PPARs signaling pathways 556

Precore region 1684

Pre-diabetes mellitus 664

Preeclampsia 1492 1513

Prehypertension 36

Previous cesarean scar defect 2080

Primary hippocampal neurons 2215

Proanthocyanidins 1486

Procyanidins 294

Prognosis 1138 1900 2198

Prognosis evaluation 1115

Programmed cell death protein 1 2301

Programmed cell death protein 4 2222

Pro-inflammatory cytokines 2203

Proliferating cell nuclear antigen 1469 1848

Prolyl isomerase 1 16

ProNGF-p75NTR 562

Propofol 245

Prostaglandin E2 983

Prostate cancer 435 1138 1257 1610 1910

Prostate specific antigen 1138

Proteasome subunit β type 8 494

Protein kinase C 1779 2062

Protein phosphatase 95

Protein phosphatase 2A 840

P-selectin glycoprotein ligand-1 1754

Psoriasis 1469

Puerariae flos 1095

Puerarin 2044

Pulmonary arterial hypertension 1724 1848

Pulmonary artery endothelial cells 346

Pulmonary fibrosis 2222 2228

Pulmonary hypertension 900 1785

Purinergic P2X7receptor 2203

Purple sweet potato 2278

Pyroptosis 969

Quercetin 206

Quercitrin 1976

Rab27agene 2113

Radiation 1990

Radioresistance 800

Radiosensitivity 631

Radiotherapy 1461

Rats 2055 2271

RAW264.7 macrophages 2127 2267

Reactive oxygen species 64 183 294 1478 1963 2256

Receiver-operating characteristic curve 664

Receptor for acvanced glycation end products 489

Receptor tyrosine kinase-like orphan receptor 2 2240

Receptor-interacting protein 2 1593

Recombinant protein 1409

Redox 183

RELMα/FIZZ1 signaling pathway 651

Renal cell carcinoma 754

Renal fibrosis 2234 2290

Renal interstitial fibrosis 672

Renal tubular epithelial cells 1076 1969

Renin-angiotensin system 36

Renin-angiotensin-aldosterone system 277

Reoxygenation 1076 1941

Reperfusion injury 399

Replication and transcription activitor 2085

Replicative senescence 1763

Restenosis 270

Resveratrol 340 346 1177 1207 1455

Reticulon 1A 2234

Retinoic acid receptor γ 778

Retinoid X receptor 2055

Rho-associated kinase 1779

Risk factors 1383

RNA interference 225 428 586 1306 1812

ROCK1 gene 729

Roscovitine 1390

Rosuvastatin 1796

Runt-related transcription factor 3 1603

RUPP rats 1513

S100Bgene 1890

S-adenosyl-L-homocysteine hydrolase 1421

Salidroside 501 1306 1478

Salvianolic acid B 482

SAM-P/8 mice 1056

SCH900776 200

Schwann cells 1527

Scientific issues 1518

SDF-1/CXCR4 signaling pathway 1177

Secretory leukocyte protease inhibitor 322

Senescence 259

Sepsis 735

Serine peptidase inhibitor clade E member 2 173

Serum amyloid A 2012

SETD2 gene 2173

Sex differences 329

SH2 domain-containing inositol 5-phosphatase 1 87

Shh signaling pathway 1969

Shh-Gli1 signaling pathway 800

Shikonin 1223 1616 1622

Short-chain acyl-CoA dehydrogenase 252

Signal transducer and activator of transcription 3 194

Signal transduction 183

Silent information regulator 1 435 712 1571

Silent information regulator 6 1827

Sinapine 918

Sinapine thiocyanate 2

Single nucleotide polymorphism 1229

Sinomenine 447 793

Sirt1/eNOS signaling pathway 259

SIRT1/eNOS/NO signaling pathway 1763

SIRT3/NLRP3 signaling pathway 969

Sitagliptin 969

Smooth muscle myosin heavy chain 1409

Snail1 940

Sodium hydrosulfide 277

Sodium valproate 1598

Sos2 protein 1835

Special AT-rich sequence-binding protein 1 1579

Specificity protein 1 141

Spermine 399

Sphingosine-1-phosphate receptor 2 2062

Spinal cord injury 862

Squamous cell carcinoma of skin 452

Staphylococcal superantigen-like protein 5 1754

STAT3 signaling pathway 87 452 1120 1233 1264 1390 1508

Stathmin 1 1120

Stem cell transplantation 2106

Streptococcus pneumoniae 322

Streptozotocin 764

Stress 1547

Stroke 572 2049

Subarachnoid hemorrhage 288

Suberoylanilide hydroxamic acid 23

Sulodexide 657

Survivin 2085

Swimming 252

Sympathetic nervous system 983 1415 1538

Sympathoexcitation 385

Synapse 2044

Synaptophysin 1905

Synergistic effect 81 447

Systemic lupus erythematosus 1890

TAL1 gene 1134

TALEN technique 2113

Tangshenfang 712

Taurine 1895

Taurine-zinc 1297

T-cell acute lymphoid leukemia 1229

T-cell receptors 2301

Telomerase reverse transcriptase 2091

Tenascin C 1884

TGFBR1 signaling pathway 833

TGF-β/BMP signaling pathways 1724

TGF-β/Smads signaling pathway 508 1324 1748

TGF-β1/Smads signaling pathway 1844

Th22 cells 1301

Thalidomide 1672

Thapsigargin 1690

The Cancer Genome Atlas 152

THP-1 cells 393

Thromboembolism 1754

Thyroid gland 335

Thyroxine 996

Tick anticoagulant peptide 1754

Tight junctions 729

TiO2 nanotube arrays 909

Tissue factor 905

Tissue inhibitor of metalloproteinase 2 1032

Tissue inhibitor of metalloproteinase-1 124

Tissue inhibitor of metalloproteinases 1770

TLR4/NF-κB signaling pathway 404 1201

T-lymphocytes 1478

TNF receptor-associated factor 6 1947

TNF-related apoptosis-inducing ligand 81

Toll-like receptor 2 322

Toll-like receptor 4 159 1702

Toll-like receptor agonists 612

Toosendanin 70

Traditional Chinese medicine Q0409 1056

Transcription factor EB 754

Transcription factors 141

Transcription regulation 1333

Transection of cervical sympathetic trunk 404

Transforming growth factor-β receptor 1730

Transforming growth factor-β1 1014 1124 1142 1501 1672 2290

Transgenic mice 335 1649

Tree shrews 2018

Trichostatin A 52

Triglyceride 1856

Tristetraprolin 288

Trophoblasts 1492

T-type calcium channels 996

Tumor budding 1900

Tumor immunity 2283

Tumor invasion 1742

Tumor metastasis 1138

Tumor microenvironment 599

Tumor necrosis factor receptor-associated factor 2 1284

Tumor necrosis factor-related apoptosis-inducing ligand 212

Tumor necrosis factor-α 346 1102 1297 1311 1390 1486 1702 2261

Tumor-infiltrating lymphocytes 1900

Tumour 173

Twist 23

Type 2 diabetes mellitus 371 489 969

Tyrosine hydroxylase 1628

Ubiquitin-specific peptidase 9 1037

Ulcerative colitis 885

Unilateral ureteral obstruction 672

Ursolic acid 464

Vascular dementia 1297 1905

Vascular development 1147

Vascular endothelial cells 1196 1223

Vascular endothelial growth factor 1002 1508 1737 2234

Vascular endothelial growth factor-A 1427

Vascular hyporeactivity 41

Vascular remodeling 252 900

Vascular smooth muscle cells 833 1306 1390

Vasoconstriction 825

Vasodilatory function 482

Ventricular remodeling 404

Viral pneumonia 2062

Virus progeny 2085

Vitamin D 10

Vitamin D receptor 2068

Vitamin D3 up-regulated protein 1 1969

Warburg effect 194

Wharton jelly 2080

White matter lesion 878

Wnt signaling pathway 232 2106

Wnt/β-catenin signaling pathway 239 410 706 778 1339 1449 2097

Wnt/β-catenin/Snail signaling pathway 1910

Wound healing 1339

Wushen-Shunmai capsule 1790

Xanthine oxidase 693

XBP1 gene 624

Xenograft tumor 786

X-linked 1037

Yangxue decoction 1469

Yangxue-Jiedu decoction 1469

Yellow wine polyphenol compounds 2133

Yes-associated protein 239

Yiqi Huayu Huatan decoction 672

Yiqi-Wenyang-Huoxue-Huatan formula 508

Zacopride 1183

Zebrafish 1067

Zerumbone 1061

Zinc finger protein 281 812

Zucker diabetic fatty rats 489

z-VAD-FMK 1653

α-Smooth muscle actin 1724 2290

α-Synuclein 1628

β cells 2240

β1-Adrenoceptor autoantibody 1922

β-Adrenergic receptors 1547

β-amyloid protein 25-35 168

β-catenin 1443

β-cell dedifferentiation 371

β-cell dysfunction 371

β-Elemene 470

β-Estradiol 1742

β-Mercaptoethanol 1427