miRNA-124 in immune system and immune disorders
2017-01-16 03:42ZhenQINPengyuanWANGDingfengSUXiaLIU
中国药理学与毒理学杂志 2017年10期
Zhen QIN,Peng-yuan WANG,Ding-feng SU,Xia LIU
(Department of Pharmacology,Second Military Medical University,Shanghai 200433,China）
T2-19
miRNA-124 in immune system and immune disorders
Zhen QIN,Peng-yuan WANG,Ding-feng SU,Xia LIU
(Department of Pharmacology,Second Military Medical University,Shanghai 200433,China）
In recent years,miR-124 has emerged as a critical modulator of immunity and inflammation.Here,we summarize studies on the function and mechanism of miR-124 in the immune system and immunity-related diseases.They indicated that miR-124 exerts a crucial role in the development of immune system,regulation of immune responses,and inflammatory disorders.It is evident that miR-124 may serve as an informative diagnostic biomarker and therapeutic target in the future.
miRNA-124;biomarker;target;immunity;immune disorders
The project supported by National Natural Science Foundation of China(grant number 81273606,81473259 to XL,81603116 to YS);and National Science and Technology Major Project(grant number 2014ZX09J14103-08C to XL)
Xia LIU,Tel:13764083416,E-mail:lxflying@aliyun.com;Ding-Feng SU,E-mail:dfsu@smmu.edu.cn
- 中国药理学与毒理学杂志的其它文章
- Pharmacological study on traditional Chinese medicine and natural product in China
- GPCRomics:tissue and cellular GPCR expression identifies new therapeutic targets
- Direction of new drug research:soft regulation of inflammatory immune responses
- Targeting Gprotein-coupled receptors for the treatment of autoimmune diseases
- Arrestin mediated GPCR biased signaling and its application in new drug discovery
- Identification of a novel target for cancer and anti-fibrotic therapy