化学工业

化学工业

封面介绍：胶原生物大分子因具有特殊的生物活性而在许多领域备受青睐.利用离子液体（IL）中阳离子可作为电子接受体而阴离子作为强氢键受体的特性来高效溶解制备胶原溶液具有广阔的应用前景.封面图给出了皮胶原在两种IL中的溶解机理.由图可见，IL中的阴阳离子对解离为自由的［BMIM］+和Cl-（Ac-）后分别与胶原肽键中的羰基氧或者—NH—上的H结合.同时由于静电力的作用，它们可分别与胶原侧链离子化的COO-与NH3+相互吸引键合.IL与胶原分子间新形成的氢键与离子键，打断了胶原分子间原有的氢键及离子键，最终导致胶原链能够自由地运动并溶解于其中.详见本期2196-2204页.

胶原在两种离子液体［BMIM］Cl和［BMIM］Ac中的溶解及再生结构比较

刘洁，赵世玉，徐洲，等

采用离子交换法，以1-丁基-3-甲基氯代咪唑（［BMIM］Cl）为原料合成了咪唑醋酸盐型离子液体（［BMIM］Ac），以两者为溶剂研究了胶原纤维在咪唑类离子液体中的溶解行为及再生前后的结构与热稳定性变化.结果表明，胶原纤维在CH3COO-和Cl-型离子液体中均能溶解，但具有明显不同的溶解特性.相对［BMIM］Cl的溶解性能而言，［BMIM］Ac能够在较低的温度下获得高浓度和良好流动性的胶原溶液，而且再生胶原的三股螺旋结构保留度更高.FTIR、UV、XRD、CD、TG分析结果表明，胶原在咪唑离子液体中溶解前后其化学结构未发生明显变化，而三股螺旋的保留度和热稳定性略有降低.

离子液体；胶原；溶解；再生；结构与性能变化

来源出版物：化工学报，2015，66（6）： 2196-2204联系邮箱：范浩军，fanhaojun@scu.edu.cn

来源出版物：Chinese Journal of Chemical Engineering，2015，23（6）： 954-961联系邮箱：WANG Jin-fu，wangjfu@tsinghua.edu.cn

封面介绍：A detailed kinetic model of the synthesis of methylphenyldichlorosilane（MPDS）from methyldichlorosilane and chlorobenzene by gas phase condensation was developed. The calculated results were in a good agreement with the experimental results. The main pathway of MPDS production was proposed and proved. The kinetic model can be used in design and optimization of the industrial reactor for MPDS synthesis（See Liu et al. Pages 954-961）.

Detailed kinetics of methylphenyldichlorosilane synthesis from methyldichlorosilane and chlorobenzene by gas phase condensation

LIU Tong ，WANG Tie-feng，HUANG Yun-long，et al.

Methylphenyldichlorosilane（MPDS，CH3C6H5SiCl2）is an important silicone monomer for the synthesis of highperformance polymethylphenylsiloxane polymers. In this work，the mechanism of the synthesis of MPDS from methyldichlorosilane and chlorobenzene by gas phase condensation was studied，and a kinetic model with 35 species and 58 elementary reactions was established. Experiments were carried out in a tubular reactor under a wide range of reaction conditions. The calculated mole fractions of the reactants and products were in a good agreement with the experimental results. A mechanism of the insertion of chloromethylsilylene into the CCl bond of chlorobenzene was proposed，which was proved to be the main pathway of MPDS production. The established kinetic model can be used in design and optimization of the industrial reactor for MPDS synthesis.

Detailed kinetics； Methylphenyldichlorosilane； Chloromethylsilylene； Gas phase condensation