211246 Factors contributing to myasthenic crisis after thymectomy—a multivariate analysis study

/Ma Jinshan(马金山，Dept Thorac Surg，Peop Hosp Xinjiang Uygur Autonom Region，Urümchi 830001)…∥Chin J Thorac Cardiovasc Surg.-2011，27(1).-27 ～29

ObjectiveTo evaluate the risk factors of myasthenic crisis(MC)after thymectomy for myasthenia gravis(MG).MethodsA retrospective study was conducted in 84 patients with MG from July 1995 to December 2009.The following factors were evaluated:sex，age，history of preoperative myasthenic crisis，Ossermen classification，steroid hormones use and anticholinesterase drugs before operation，operation methods，operation time，thymoma，pathology，transfusion，course of disease，postopertive lung infection，etc.Multivariate logistic regrossion analysis was used to find the predictors of postoperative myasthenic crisis.ResultsTwenty-four patients(28.6%)developed myasthenic crisis after thymectomy.Statistics showed that history of preoperative myasthenic crisis，Ossermen classification，operation methods，operation time were related to postoperative myasthenic crisis.ConclusionPreoperative myasthenic crisis，Ossermen classification≥I b，traditional operation methods，long operation time are the independent risk factors for myasthenic crisis after thymectomy.11 refs，2 tabs.