Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease published

Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease published

Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease(ISBN:978-3-662-46343-7,eBook ISBN: 978-3-662-46344-4)was published by Springer⁃Verlag Berlin Heidelberg in May 2015.The editors of this book are Hoa Huu Phuc Nguyen(Institute of Medical Genetics and Applied Genomics,University of Tuebingen)and M.Angela Cenci(Department of Experimental Medical Science,Lund University).

Motor dysfunction and cognitive impairment are major symptoms in both Huntington's disease(HD)and Parkinson's disease (PD).A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly,several genes were found to cause familial forms of PD.With their identification,a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders.The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time.Additionally,neurotoxic animal models are still of high interest to the PD field,as they are being used to study e.g.mitochondrial dysfunction in PD.This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.

The price of eBook is 118.99€,and hardcover is 149.99€.Visit link.springer.com for more information.