Ultrasound measurement of the corpus callosum and neural development

LETTERS TO THE EDITOR

Ultrasound measurement of the corpus callosum and neural development

Sir, the recent report on “ultrasound measurement of the corpus callosum and neural development” is very interesting[1]. Liu et al. reported that “corpus callosum growth in premature infants is associated with neurobehavioral development during the early extrauterine stage[1].” In fact, the use of 3D ultrasound seems to be useful to determine corpus callosum abnormality[2]. However, the genetic counseling based on its result remains controversial[2]. Santo et al. found that normal outcome could be observed in about 65–75% of cases with detected abnormalities of corpus callosum[3]. The diagnostic sensitivity of the ultrasound is also the topic to be considered[4]. Inaccuracy of ultrasound can be commonly seen and this leads to the requirement of additional MRI investigation[5].

[1] Liu F, Cao S, Liu J, Du Z, Guo Z, Ren C. Ultrasound measurement of the corpus callosum and neural development of premature infants. Neural Regen Res 2013;8:2432-2440.

[2] De Catte L, De Keersmaeker B, Claus F. Prenatal neurologic anomalies: sonographic diagnosis and treatment. Paediatr Drugs. 2012;14:143-155.

[3] Santo S, D’Antonio F, Homfray T, Rich P, Pilu G, Bhide A, Thilaganathan B, Papageorghiou AT. Counseling in fetal medicine: agenesis of the corpus callosum. Ultrasound Obstet Gynecol. 2012;40:513-521.

[4] Karl K, Kainer F, Heling KS, Chaoui R. Fetal neurosonography: extended examination of the CNS in the fetus. Ultraschall Med. 2011;32:342-361.

[5] Wald M, Lawrenz K, Deutinger J, Weninger M. Veri fi cation of anomalies of the central nervous system detected by prenatal ultrasound. Ultraschall Med. 2004;25:214-217.

Professor Viroj Wiwanitkit, M.D., Hainan Medical University, China.

Accepted: 2014-01-04

Wiwanitkit V. Ultrasound measurement of the corpus callosum and neural developmeng. Neural Regen Res. 2014;9(3):336.

Viroj Wiwanitkit, M.D., Hainan Medical University, China, wviroj@yahoo.com.

10.4103/1673-5374.128233 http://www.nrronline.org/